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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBX6
All Species:
8.18
Human Site:
T298
Identified Species:
15
UniProt:
O95947
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95947
NP_004599.2
436
47045
T298
R
G
P
E
P
A
A
T
E
A
Y
G
S
G
D
Chimpanzee
Pan troglodytes
XP_523337
436
47083
A298
R
C
P
E
P
A
A
A
E
A
Y
G
S
G
D
Rhesus Macaque
Macaca mulatta
XP_001098963
496
53657
P307
A
Y
G
S
G
A
Q
P
L
P
S
L
S
P
D
Dog
Lupus familis
XP_547068
436
47185
A298
R
V
P
E
P
I
A
A
E
A
Y
G
S
G
D
Cat
Felis silvestris
Mouse
Mus musculus
P70327
540
58610
T298
R
G
P
E
P
V
A
T
E
A
C
G
S
G
D
Rat
Rattus norvegicus
Q5I2P1
517
57726
R374
Y
R
T
E
S
A
Q
R
Q
A
C
M
Y
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520749
277
31432
I148
R
L
P
D
R
V
Y
I
H
P
D
S
P
A
T
Chicken
Gallus gallus
P79779
361
41167
K232
P
S
P
A
K
G
Q
K
R
K
L
P
E
E
K
Frog
Xenopus laevis
Q8AV66
506
56540
M281
K
G
F
R
E
D
G
M
K
S
K
R
D
R
S
Zebra Danio
Brachydanio rerio
P79742
473
53459
S278
R
D
T
Q
N
S
S
S
V
S
L
N
P
F
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
L548
V
S
S
S
R
A
P
L
H
L
G
H
A
G
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
T291
N
S
E
D
D
E
P
T
L
K
K
C
K
P
E
Sea Urchin
Strong. purpuratus
XP_797010
645
70075
S392
S
S
G
E
A
S
G
S
Q
L
T
C
T
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
81.8
90.1
N.A.
64.4
34.8
N.A.
43.8
35
43
37
N.A.
22.8
N.A.
35.5
30.2
Protein Similarity:
100
99
83.2
92.1
N.A.
67.9
48.5
N.A.
48.3
47.4
54.5
52.8
N.A.
30.7
N.A.
52.5
43.8
P-Site Identity:
100
86.6
20
80
N.A.
86.6
20
N.A.
13.3
6.6
6.6
6.6
N.A.
13.3
N.A.
6.6
6.6
P-Site Similarity:
100
86.6
20
80
N.A.
86.6
26.6
N.A.
20
6.6
26.6
40
N.A.
20
N.A.
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
39
31
16
0
39
0
0
8
16
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
16
16
0
0
0
% C
% Asp:
0
8
0
16
8
8
0
0
0
0
8
0
8
0
39
% D
% Glu:
0
0
8
47
8
8
0
0
31
0
0
0
8
8
8
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
24
16
0
8
8
16
0
0
0
8
31
0
39
0
% G
% His:
0
0
0
0
0
0
0
0
16
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
8
% I
% Lys:
8
0
0
0
8
0
0
8
8
16
16
0
8
0
8
% K
% Leu:
0
8
0
0
0
0
0
8
16
16
16
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% M
% Asn:
8
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
8
0
47
0
31
0
16
8
0
16
0
8
16
16
8
% P
% Gln:
0
0
0
8
0
0
24
0
16
0
0
0
0
0
0
% Q
% Arg:
47
8
0
8
16
0
0
8
8
0
0
8
0
8
8
% R
% Ser:
8
31
8
16
8
16
8
16
0
16
8
8
39
8
16
% S
% Thr:
0
0
16
0
0
0
0
24
0
0
8
0
8
0
8
% T
% Val:
8
8
0
0
0
16
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
8
0
0
0
24
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _